Usa-Places.com has listed approx 18 wineries in San Luis Obispo. Some of the Top rated wineries in San Luis Obispo are- Tolosa, Edna Valley Vineyard, Baileyana Tangent & True Myth Tasting Room, Sextant Wines, Claiborne & Churchill Winery, Chamisal Vineyards, Biddle Ranch Vineyard, Autry Cellars, Stephen Ross Wine Cellars & Croma Vera Wines.